Double-Balloon Enteroscopy: A New Approach for Suspected Small-Bowel Bleeding

This new technique showed promise in two studies.

Because radiographic studies have poor sensitivity for detecting small-bowel sources of gastrointestinal bleeding, new techniques have been developed. Video capsule endoscopy is a major advance, but it doesn't allow for biopsies or therapeutic interventions. A new approach is double-balloon enteroscopy (also called "push-and-pull enteroscopy"). Balloons are attached to the distal ends of both an enteroscope and a transparent tube that slides over it. The balloons can be inflated to "grip" the small intestine and pull it over the instrument, allowing visualization of long portions of small bowel. The device can be inserted orally or anally to visualize proximal or distal small bowel, respectively.

Two studies demonstrate the yield of this technique in patients for whom upper endoscopy and colonoscopy failed to reveal a source of GI bleeding. In a study from China, double-balloon enteroscopy revealed a potential bleeding source in 76% of 152 patients, most commonly angiodysplasia and small-bowel tumors. In a study from Germany, the diagnostic yield among 52 patients was 73% (vs. a 44% diagnostic yield with a conventional push enteroscope); mean insertion depth was 230 cm via the oral route. In both studies, argon plasma coagulation was used to treat sources of bleeding. No serious complications were reported in either study.

Comment: Double-balloon enteroscopy is a promising new approach to the diagnosis and treatment of small-bowel sources of bleeding. The procedure is currently available only at a handful of U.S. centers, but that is likely to change. A short video depicting use of the double-balloon enteroscope can be viewed online free of charge.

— Allan S. Brett, MD

Published in Journal Watch October 24, 2006

Citation(s):

Sun B et al. Diagnostic yield and therapeutic impact of double-balloon enteroscopy in a large cohort of patients with obscure gastrointestinal bleeding. Am J Gastroenterol 2006 Sep; 101:2011-5.